abstract：:Exposure to arsenic via drinking water is considered as a worldwide problem. Studies have shown that arsenic exposure during pregnancy affects embryogenesis and offspring development in rats and mice. Zinc as a micronutrient regulates many physiological functions, including an antioxidative role under various toxic co...

journal_title：Biological research

authors： Ahmad M,Wadaa MA,Farooq M,Daghestani MH,Sami AS

更新日期：2013-01-01 00:00:00

abstract：:Oxidant/antioxidant imbalance has been reported in some infectious diseases, including community-acquired pneumonia (CAP). The aim was to assess the antioxidant status in adults with CAP and its relationship with clinical severity at admission. Fifty-nine patients with CAP were enrolled and categorized at admission by...

journal_title：Biological research

authors： Castillo RL,Carrasco RA,Alvarez PI,Ruiz M,Luchsinger V,Zunino E,Martínez MA,Avendaño LF

更新日期：2013-01-01 00:00:00

abstract：:The hypothesis that the vacation-study-expectancy scholar regime produces most of the monthly rhythm of the age at menarche (AaM) was tested. Studies on monthly menarche incidence (MI) refuted climatic factors as a main factor in this rhythm, and indicated that the main factor of this rhythm is the succession of expec...

journal_title：Biological research

authors： Valenzuela CY

更新日期：2013-01-01 00:00:00

abstract：:The anti-tumor effect of R-Phycoerythrin (R-PE) from Porphyra haitanensis was studied using cell line HeLa as an in vitro model and Sarcoma-180 (S180) tumor-bearing mice as an in vivo model. The results showed that the combination treatment of R-PE and photodynamic therapy PDT) significantly inhibited the growth of He...

journal_title：Biological research

authors： Pan Q,Chen M,Li J,Wu Y,Zhen C,Liang B

更新日期：2013-01-01 00:00:00

abstract：:Interstitial fluid flow stress is one of the most important mechanical stimulations of bone cells under physiological conditions. Osteocytes and osteoblasts act as primary mechanosensors within bones, and in vitro are able to respond to fluid shear stress, both morphologically and functionally. However, there is littl...

journal_title：Biological research

authors： Xu H,Zhang J,Wu J,Guan Y,Weng Y,Shang P

更新日期：2012-01-01 00:00:00

abstract：:Loss of Imprinting (LOI) of IGF2 and over-expressed IGF2 are associated with tumorigenesis. Our previous epidemiological study found a relatively high frequency of IGF2 LOI in healthy mid-gestation pregnant women. The aim of this study is to determine whether the expression of IGF2 is associated with its imprinting st...

journal_title：Biological research

authors： Ru-Fei G,Xue-Qing L,Ying-Xiong W,Xue-Mei C,Yu-Bin D,Jun-Lin H

更新日期：2012-01-01 00:00:00

abstract：:The historical, lexical and conceptual issues embedded in stem cell biology are reviewed from technical, ethical, philosophical, judicial, clinical, economic and biopolitical perspectives. The mechanisms assigning the simultaneous capacity to self-renew and to differentiate to stem cells (immortal template DNA and asy...

journal_title：Biological research

authors： Monti M,Perotti C,Del Fante C,Cervio M,Redi CA,Fondazione IRCCS Policlinico San Matteo, Pavia (Italia).

更新日期：2012-01-01 00:00:00

abstract：:Hematopoietic stem cell transplantation is the accepted therapy of choice for a variety of malignant and non-malignant diseases in children and adults. Initially developed as rescue therapy for a patient with cancer after high doses of chemotherapy and radiation as well as the correction of severe deficiencies in the ...

journal_title：Biological research

authors： Barriga F,Ramírez P,Wietstruck A,Rojas N

更新日期：2012-01-01 00:00:00

abstract：:Shigella flexneri causes bacillary dysentery in humans. Essential to the establishment of the disease is the invasion of the colonic epithelial cells. Here we investigated the role of the lipopolysaccharide (LPS) O antigen in the ability of S. flexneri to adhere to and invade polarized Caco-2 cells. The S. flexneri 2a...

journal_title：Biological research

authors： Hoare A,Bravo D,Martinić M,Valvano MA,Contreras I,Álvarez SA

更新日期：2012-01-01 00:00:00

abstract：:After the progress made during the genomics era, bioinformatics was tasked with supporting the flow of information generated by nanobiotechnology efforts. This challenge requires adapting classical bioinformatic and computational chemistry tools to store, standardize, analyze, and visualize nanobiotechnological inform...

journal_title：Biological research

authors： González-Nilo F,Pérez-Acle T,Guínez-Molinos S,Geraldo DA,Sandoval C,Yévenes A,Santos LS,Laurie VF,Mendoza H,Cachau RE

更新日期：2011-01-01 00:00:00

abstract：:The anti-inflammatory and redox protective effects of the citronellal (CT) were evaluated using in vivo and in vitro tests. Intraperitoneal (i.p.) administration of CT (50, 100, and 200 mg/kg) inhibited (p < 0.05) the carrageenan-induced leukocyte migration to the peritoneal cavity. Additionally, the carrageenan- and ...

journal_title：Biological research

authors： Melo MS,Guimarães AG,Santana MF,Siqueira RS,De Lima Ado C,Dias AS,Santos MR,Onofre AS,Quintans JS,De Sousa DP,Almeida JR,Estevam CS,Araujo BS,Quintans-Júnior LJ

更新日期：2011-01-01 00:00:00

abstract：:The species Heteropterys aphrodisiaca is commonly used as a stimulant by popular medicine in the Cerrado, a savanna-like biome, Brazil. Recent studies have proved its protective effects on testes of animals submitted to treatment using Cyclosporine A, as well as its stimulus effect in increasing testosterone secretion...

journal_title：Biological research

authors： Gomes ML,Monteiro JC,Freitas KM,Sbervelheri MM,Dolder H

更新日期：2011-01-01 00:00:00

abstract：:In this article, we focus on the fundamental role of vitamin C transporters for the normal delivery of vitamin C to germ cells in the adluminal compartment of seminiferous tubules. We argue that the redox status within spermatozoa or in semen is partly responsible for the etiology of infertility. In this context, anti...

journal_title：Biological research

authors： Angulo C,Maldonado R,Pulgar E,Mancilla H,Córdova A,Villarroel F,Castro MA,Concha II

更新日期：2011-01-01 00:00:00

abstract：:The aim of this study was to investigate the in vitro cytotoxic activity of total extract of MeOH (70%) and partition fractions of hexan, chloroform (CHCL3), ethylacetate (EtOAc) and MeOH-H2O of brown algae species (Sargassum swartzii, Cystoseira myrica, Colpomenia sinuosa) found in the Persian Gulf against in differe...

journal_title：Biological research

authors： Khanavi M,Nabavi M,Sadati N,Shams Ardekani M,Sohrabipour J,Nabavi SM,Ghaeli P,Ostad SN

更新日期：2010-01-01 00:00:00

abstract：:7-ketocholesterol (7-KC) differs from cholesterol by a functional ketone group at C7. It is an oxygenated cholesterol derivative (oxysterol), commonly present in oxidized low-density lipoprotein (LDL). Oxysterols are generated and participate in several physiologic and pathophysiologic processes. For instance, the cyt...

journal_title：Biological research

authors： Favero GM,Maranhão RC,Maria DA,Levy D,Bydlowski SP

更新日期：2010-01-01 00:00:00

abstract：:Thymulin is a well-characterized thymic hormone that exists as a nonapeptide coupled to equimolar amounts of Zn2+. Thymulin is known to have multiple biological roles, including T cell differentiation, immune regulation, and analgesic functions. It has been shown that thymulin is produced by the reticulo-epithelial ce...

journal_title：Biological research

authors： Folch H,Villegas JV,Leyan V,Barría M,Eller G,Esquivel P

更新日期：2010-01-01 00:00:00

abstract：:Extracts prepared from seeds of Manilkara zapota, Anona squamosa, and Tamarindus indica were screened for their antibacterial activity by disc diffusion and broth dilution methods. Acetone and methanol extracts of T. indica seeds were found active against both gram-positive and gram-negative organisms. MIC values of p...

journal_title：Biological research

authors： Kothari V,Seshadri S

更新日期：2010-01-01 00:00:00

abstract：:Object recognition memory allows discrimination between novel and familiar objects. This kind of memory consists of two components: recollection, which depends on the hippocampus, and familiarity, which depends on the perirhinal cortex (Pcx). The importance of brain-derived neurotrophic factor (BDNF) for recognition m...

journal_title：Biological research

authors： Muñoz PC,Aspé MA,Contreras LS,Palacios AG

更新日期：2010-01-01 00:00:00

abstract：:Although several histone variants have been studied in both animal and plant organisms, little is known about their distribution during processes that involve alterations in chromatin function, such as differentiation, dedifferentiation and hormone treatment. In this study we evaluated the ratio of each histone varian...

journal_title：Biological research

authors： Alatzas A,Foundouli A

更新日期：2009-01-01 00:00:00

abstract：:The aim of this study is to describe the ultrastructural changes of the egg apparatus associated with fertilisation of the natural tetraploid Trifolium pratense. The pollen tube enters one of the synergids through the filliform apparatus from the micropyle. Before the entry of the pollen tube into the embryo sac, one ...

journal_title：Biological research

authors： Buyukkartal HN

更新日期：2009-01-01 00:00:00

abstract：:Skeletal muscles have the potential to regenerate by activation of quiescent satellite cells, however, the molecular signature that governs satellite cells during muscle regeneration is not well defined. Myosin light chains (Myls) are sarcomere-related proteins as traditional regulator of muscle contraction. In this r...

journal_title：Biological research

authors： Zhang SZ,Xu Y,Xie HQ,Li XQ,Wei YQ,Yang ZM

更新日期：2009-01-01 00:00:00

abstract：:Hyptidendron canum (Pohl ex Benth.) Harley is a native tree of the Brazilian Savannah. The fish Oreochromis niloticus L. was used as an experimental model to determine the bioactivity of the crude ethanol extract as well as ethyl acetate, hexanic and chloroform fractions obtained from its leaves. The plant ethanol ext...

journal_title：Biological research

authors： Fiuza TS,Silva PC,Paula JR,Tresvenzol LM,Sabóia-Morais SM

更新日期：2009-01-01 00:00:00

abstract：:The objective of this study was to test the hypothesis that root of maguey (Agave salmiana Otto ex Salm-Dyck) seedlings reacts during the first 24 h to low substrate water potential (PsiW), by anatomical modifications. Three-4 cm root length seedlings were planted in vermiculite for 24 h at PsiW between -0.03 and -2.3...

journal_title：Biological research

authors： Peña-Valdivia CB,Sánchez-Urdaneta AB

更新日期：2009-01-01 00:00:00

abstract：:The ascorbate-glutathione (ASC-GSH) cycle has an important role in defensive processes against oxidative damage generated by drought stress. In this study, the changes that take place in apoplastic and symplastic ASC-GSH cycle enzymes of the leaf and petiole were investigated under drought stress causing leaf rolling ...

journal_title：Biological research

authors： Saruhan N,Terzi R,Saglam A,Kadioglu A

更新日期：2009-01-01 00:00:00

abstract：:Many motor skills, once acquired, are stored over a long time period, probably sustained by permanent neuronal changes. Thus, in this paper we have investigated with quantitative stereology the generation and persistence of neuronal density changes in primary motor cortex (MI) following motor skill learning (skilled r...

journal_title：Biological research

authors： Morales P

更新日期：2008-01-01 00:00:00

abstract：:The purpose of this study was to carry out a bibliometric analysis of the articles published in Chile during 1987-2006 that were categorized into the Plant Science discipline by ISI. The data was extracted from the Web of Science datábase, obtaining a total of 911 articles for analysis. Almost half of the articles wer...

journal_title：Biological research

authors： Krauskopf E

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The characterization of the dynamic process of veins walls is essential to understand venous functioning under normal and pathological conditions. However, little work has been done on dynamic venous properties. AIM:To characterize vein compliance (C), viscosity (eta), peak-strain (W St) and dissipated (W(D...

journal_title：Biological research

authors： Zócalo Y,Bia D,Lluberas S,Armentano RL

更新日期：2008-01-01 00:00:00

abstract：:In the last few decades, several works on event related potentials (ERPs hereafter) during sleep have been reported. In spite of numerous studies, clear methodological rules for this kind of study are often missing, making it difficult to valorize the scope of these results. We propose here a description of methodolog...

journal_title：Biological research

authors： Ibáñez AM,San Martín R,Hurtado E,López V

更新日期：2008-01-01 00:00:00

abstract：:The regeneration of natural tetraploid T. pratense, originated from Erzurum-Turkey, is reported in this study. This plant has low seed setting and hard seed problems due to polyploidy. Hypocotyl, cotyledon, apical meristems, epicotyl and young primary leaves were inoculated on MS and PC-L2 media containing different c...

journal_title：Biological research

authors： Cölgeçen H,Toker MC

更新日期：2008-01-01 00:00:00

abstract：:In the last twenty years an important effort in brain sciences, especially in cognitive science, has been the development of mathematical tool that can deal with the complexity of extensive recordings corresponding to the neuronal activity obtained from hundreds of neurons. We discuss here along with some historical i...

journal_title：Biological research

authors： Goles E,Palacios AG

更新日期：2007-01-01 00:00:00

abstract：:The radiobiocomplexes labeled with technetium-99m (Tc-99m) have been widely used in nuclear medicine in single photon emission computed tomography and in basic research. The aim of this study was to assess the influence of a Nectandra membranacea extract on the bioavailability of the sodium pertechnetate (Na(99m)TcO(4...

journal_title：Biological research

authors： Moreno SR,Arnobio A,De Carvalho JJ,Nascimento L,Oliveira Timoteo M,Olej B,Rocha EK,Pereira M,Bernardo-Filho M,Caldas LQ

更新日期：2007-01-01 00:00:00

abstract：:Peroxisomes are thought to be formed by division of pre-existing peroxisomes after the import of newly synthesized proteins. However, it has been recently suggested that the endoplasmic reticulum (ER) provides an alternative de novo mechanism for peroxisome biogenesis in some cells. To test a possible role of the ER-G...

journal_title：Biological research

authors： Toro A,Arredondo C,Córdova G,Araya C,Palacios JL,Venegas A,Morita M,Imanaka T,Santos MJ

更新日期：2007-01-01 00:00:00

abstract：:Although evidence is accumulating that prenatal testosterone (T) compromises reproductive function in the female, the effects of excess T in utero on the postnatal development of male reproductive function has not been studied. The aim of this study was to assess the influence of prenatal T excess on age-related chang...

journal_title：Biological research

authors： Recabarren SE,Lobos A,Figueroa Y,Padmanabhan V,Foster DL,Sir-Petermann T

更新日期：2007-01-01 00:00:00

abstract：:Compared with morphological and life history traits, quantitative genetic variation of metabolic and related traits in animals has been poorly studied. We used flow-through VCO(2) respirometry and simultaneous activity measurement on nymphs of the sand cricket (Gryllus firmus) from inbred lines to estimate broad-sense...

journal_title：Biological research

authors： Nespolo RF,Castañeda LE,Roff DA

更新日期：2007-01-01 00:00:00

abstract：:Oxidative stress occurs early in the progression of Alzheimer disease, significantly before the development of the pathologic hallmarks, neurofibrillary tangles and senile plaques. In the first stage of development of the disease, amyloid-beta deposition and hyperphosphorylated tau function as compensatory responses a...

journal_title：Biological research

authors： Moreira PI,Zhu X,Liu Q,Honda K,Siedlak SL,Harris PL,Smith MA,Perry G

更新日期：2006-01-01 00:00:00

abstract：:Brain cells have a highly active oxidative metabolism, yet they contain only low to moderate superoxide dismutase and catalase activities. Thus, their antioxidant defenses rely mainly on cellular reduced glutathione levels. In this work, in cortical neurons we characterized viability and changes in reduced and oxidize...

journal_title：Biological research

authors： Aguirre P,Mena N,Tapia V,Rojas A,Arredondo M,Núñez MT

更新日期：2006-01-01 00:00:00

abstract：:Hepcidin (Hepc) is a 25 amino acid cationic peptide with broad antibacterial and antifungal actions. A likely role for Hepc in iron metabolism was suggested by the observation that mice having disruption of the gene encoding the transcription factor USF2 failed to produce Hepc mRNA and developed spontaneous visceral i...

journal_title：Biological research

authors： Mena NP,Esparza AL,Núñez MT

更新日期：2006-01-01 00:00:00

abstract：:The electrophysiological properties of neurons are determined by the expression of defined complements of ion channels. Nonetheless, the regulation mechanisms of the expression of neuronal ion channels are poorly understood, due in part to the diversity of neuron subtypes. We explored the expression of voltage-gated c...

journal_title：Biological research

authors： Olguín P,Armisen R,Kukuljan M

更新日期：2006-01-01 00:00:00

abstract：:The neuropeptide oxytocin (OXT) is a key factor in the initiation and regulation of sociosexual behavior. The present study analyzes the effects of cohabitation and social challenge on plasma OXT concentration rates in guinea pig pairs in relation to male sociosexual behavior. The cohabitation phase lasted 3 days. On ...

journal_title：Biological research

authors： Wallner B,Dittami J,Machatschke I

更新日期：2006-01-01 00:00:00

abstract：:The protein nucleolin, functionally involved in the main steps of ribosome biogenesis, is codified by a single copy gene in mammals. Here we report that at least three different genes codify for this protein in carp fish (Cyprinus carpio). This is the first description of the genomic organization of nucleolin in a tel...

journal_title：Biological research

authors： Quezada C,Navarro C,San Martín R,Alvarez M,Molina A,Vera MI

更新日期：2006-01-01 00:00:00